Homocysteine Nutrients  by Seeking Health supplies bioactive forms of four essential B-vitamins together with betaine (also known as trimethylglycine or TMG) to synergistically support methylation processes and normal homocysteine metabolism. The body's methylation process is vital for formation of essential cell components such as proteins, nucleic acids found in DNA and RNA, and phospholipids that form nerve cell membranes. By transferring methyl groups (three hydrogen atoms bonded to a carbon atom, known as CH3) from one molecule to another, methylation turns on genes, activates enzymes, drives detoxification reactions, influences hormone secretion, and helps maintain normal metabolism of homocysteine, a potentially harmful amino acid metabolite. Unfortunately, poor nutrition, oxidative stress, infections, metabolic defects, and various other factors can impair methylation processes throughout the body.*

To nutritionally support optimal methylation capacity, this product supplies folate, vitamin B12, B6, B2, and betaine in amounts and forms that are efficiently utilized and well-tolerated by the body. Taking just L-5-methylfolate is often times not sufficient for those with MTHFR mutations. Dr. Lynch provides these other ingredients, such as betaine (TMG), to help support healthy homocysteine levels and support the methylation cycle.*

Betaine is a powerful and important methyl donor for the body, especially for those who have MTHFR mutations. Vitamin B12 is crucial to the formation of healthy red blood cells, energy production, nervous system support, cognitive function, and homocysteine regulation. Vitamin B6 as P-5-P is important as a coenzyme for the normal metabolism of amino acids, carbohydrates and lipids. It is also involved in healthy cognitive development, immune health and homocysteine conversion. Riboflavin is important for body growth and red blood cell production and assists in the process of releasing energy from carbohydrates.*

For a methylation support supplement without the betaine, consider our HomocysteX. For a B12- and folate-only product, consider our Active B12 with L-5-MTHF or our Optimal Liposomal Active B12 with L-5-MTHF.

Key Benefits and Actions*

• Provides active B vitamins in potent doses
• May help support healthy methylation processes
• May help support normal homocysteine conversion
• May help support cognitive health